MDE → CLO
Flights from Medellín to Cali
Medellín to Cali (MDE–CLO) is a nonstop domestic air route within Colombia. It is served nonstop by 3 airlines. Use Flyroz to compare live fares, then book directly with the airline or travel site — we never add a booking fee.
Cheapest one-way from
Search to see current fares for your dates.
How long is the flight?
Nonstop flights from Medellín (MDE) to Cali (CLO) take roughly 0h 47m–0h 56m in the air, estimated from the ~310 km great-circle distance. This is an estimate, not a published block time — exact times vary by aircraft, routing and conditions.
Airlines flying this route
Nonstop MDE–CLO service is operated by Avianca, JetSmart and LATAM. Carriers were verified against FlightConnections (accessed 2026-07-13); schedules change over time, so check current results for your dates.
Direct vs. connecting flights
This is a domestic nonstop route. Nonstop is fastest; one-stop connecting itineraries via Bogotá or another Colombian hub are sometimes cheaper but add hours. Run a live search to compare.
Best time to fly & book
Fares tend to be higher around Colombian holidays, Semana Santa (Easter week) and the year-end peak, and lower in the shoulder seasons. Booking a few weeks ahead and keeping dates flexible generally gives more choice.
Frequently asked questions
Is there a nonstop flight from Medellín to Cali?
Yes — MDE–CLO is served nonstop by Avianca, JetSmart and LATAM. Run a live search to compare fares on your dates.
How long is the flight from Medellín to Cali?
Nonstop flights take roughly 0h 47m–0h 56m in the air (a great-circle estimate; exact times vary by aircraft and conditions).
Which airlines fly nonstop from Medellín to Cali?
Nonstop service is operated by Avianca, JetSmart and LATAM. Schedules change, so confirm current options with a live search.
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